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Principal Investigator, Scientific Data Engineer
  • Python
  • Java
  • Linux
  • Excel
  • Database
  • Data Mining
  • C#
Incyte Corporation
Wilmington, DE 19803
137 days ago

Incyte is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology and inflammation and autoimmunity. Incyte is committed to the rigorous pursuit of research and development excellence to improve the lives of patients, make a difference in health care, and build sustainable value.

The Company strives to discover and develop first-in-class and best-in-class medicines-advancing a diverse portfolio of large and small molecules.

Job Summary (Primary function)

As part of our continued investment in discovery research, we are currently seeking an outstanding scientific data engineer with proven experience extracting insights from complex biological and chemical data for drug discovery in a Biotech or Pharma R&D environment. Using a broad range of programming and scientific computing methods, the successful individual will enable data mining and pattern recognition across discovery biology with an emphasis on complex biological assays (e.g. high content imaging, HTS campaigns, compound profiling for lead optimization and structural biology).

The successful candidate will also function as a scientific and technical expert for the drug discovery organization with responsibility for scouting and developing and integrating new data technology into the drug discovery process. Expertise in scientific computing, modelling, data management, and programming is required.

Key Job Responsibilities

  • Provide cross-departmental scientific leadership for data management and analysis.
  • Develop and maintain tools for HTS compound annotation, data curation and analysis.
  • Enable Structural Biology data flows and analysis.
  • Enable new scientific insights through the analysis of large experimental datasets integrated with diverse biological and chemical data.
  • Enable high content image analysis
  • Contribute to strategic planning and implementation of preclinical data logistics.

Minimum Requirements

  • PhD in Data Sciences or in a biomedical field with specialization in data sciences.
  • 8+ years’ experience in scientific data engineering and scientific computing within preclinical pharmaceutical research.
  • Advanced Linux system and data management skills, especially REDHAT Enterprise Linux.
  • Advanced shell scripting skills including bash/tcsh/csh/zsh.
  • Knowledge of AWS cloud platforms and other containerized systems such as VMWARE.
  • Knowledge of crystallographic and CryoEM data processing pipelines and software including PHENIX, CCP4, CryoSparc and Relion.
  • Oracle database development skills.
  • Knowledge of other programming/scripting languages a plus (Python, VB.NET, ASP.NET, C#, Javascript, Java).
  • A track record of success in contributing to and advancing early drug discovery programs to identify clinical candidates is preferred.

Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.


Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer.

We Respect Your Privacy

Learn more at: http://www.incyte.com/privacy-policy

The Incyte hiring organization processes your personal data to manage your job application in order to enter into an employment relationship with you if you are the successful candidate.

During the process, you may be asked to respond to questions that will screen out your application if you do not meet certain objective criteria required by the job. You can learn more about this process here.

You may have the right to access, delete, restrict, edit, move, or object to the use of your personal data. You may also have a right to report concerns to the authority responsible for data privacy in the country where the position is based or where you live or work.

You can learn more about Incyte’s data protection practices here. By accessing this link you can learn about the types of personal data we collect, how we use it, whether collection and processing is optional, sources of the personal data we process, how it is shared, where it is stored or transferred to, how long we keep it, and contact information for Incyte, Incyte’s data protection officer, and your supervisory authority (if applicable).

Please contact privacy@incyte.com if you have any questions or concerns or would like to exercise your rights.

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