Bioinformatician/Data Scientist

Location: Sutton

*** Mention DataYoshi when applying ***

We are seeking an individual with an exceptional track-record in using data to address important clinical/scientific questions, having excellent analytical skills but also broader skills in conceptualisation, project management, write-up and delivery.

The post is part of the £4.3 million CRUK-funded CanGene-CanVar program (, led by Professor Turnbull at the ICR, Prof Tischkowitz (University of Cambridge) and Prof Eccles (University of Southampton). This large program has been designed to produce research and resources that will improve how we deliver national NHS testing for cancer susceptibility genes such as BRCA1, BRCA2 and Lynch Syndrome genes. It will involve working with a large team of scientists, clinicians and patients highly passionate about achieving this goal.

This complex program of work involves 16 PIs from six Higher Education Institutes (ICR, Cambridge, Southampton, Manchester, Oxford and St George’s University London) as well as Public Health England (Health Data Insight).

The post is situated in the ICR Variant Interpretation Team (Work Package 2), within the Division of Genetics and Epidemiology in the laboratory of Professor Clare Turnbull. Working alongside a clinical scientist (with background in variant interpretation for diagnostics), a software-engineer, a bioinformatician, and two clinical fellows, the post holder will be responsible for undertaking analyses to better understand variation in cancer susceptibility genes.

The post holder will interface regularly with the UK NHS clinical and diagnostic laboratory community to identify topical challenges in how evidence is applied to interpret genomic variants identified on clinical testing. Deploying statistical, bioinformatic and machine-learning approaches, the postholder will undertake novel analyses of UK laboratory, publicly available and collaborator-shared variant data to address these questions.

We anticipate the post will be suitable for someone coming from a background in research, who is interested in moving towards clinical/diagnostic bioinformatics. Or someone from clinical/diagnostic bioinformatics who is seeking to undertake research work in an academic setting.

The post is based at ICR Sutton. For the right candidate, we are very open to flexible daily/weekly work-patterns, including part-time/part-home working. Occasional UK/international travel may be required.

More details are available within the job description and person specification. Informal enquiries are welcome and can be made to Professor Clare Turnbull by emailing Please note – this address is for enquiries only and applications must be submitted on-line, via the e-recruitment system.

We consider all applications on merit and have a strong commitment to enhancing the diversity of our staff.

The ICR is the leading academic research centre in the UK. Effective industry collaboration and innovation in new medicines and technologies are at the heart of our approach to drive benefits for patients. The ICR is ranked:

  • first for the quality and impact of our research*
  • second worldwide for the number of our publications cited in patents**
  • fourth worldwide for the citation rate of scientific research published across all fields**
  • fourth worldwide for top-cited research publications**
  • in the top five higher education institutions worldwide for academic influence and commercial impact**

  • 2014 Research Excellence Framework

** U-Multirank, 2020

*** Mention DataYoshi when applying ***

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